E6446 (dihydrochloride)
- Product Name
- E6446 (dihydrochloride)
- CAS No.
- 1345675-25-3
- Chemical Name
- E6446 (dihydrochloride)
- Synonyms
- CS-2089;E6446 HCl;E6446 2HCl;E-6446 DihydrochL;E6446;E 6446;E-6446;E6446 hydrochloride;E6446 (dihydrochloride);E6446 dihydrochloride,E-6446 dihydrochloride;6-(3-(Pyrrolidin-1-yl)propoxy)-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)benzo[d]oxazole dihydrochloride
- CBNumber
- CB53041403
- Molecular Formula
- C27H36ClN3O3
- Formula Weight
- 486.05
- MOL File
- 1345675-25-3.mol
E6446 (dihydrochloride) Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- DMSO:7.5(Max Conc. mg/mL);14.35(Max Conc. mM)
DMF:20.0(Max Conc. mg/mL);38.28(Max Conc. mM)
DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.38(Max Conc. mM)
Ethanol:2.0(Max Conc. mg/mL);3.83(Max Conc. mM)
Water:100.0(Max Conc. mg/mL);191.38(Max Conc. mM)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 3422DW
- Product name
- E6446(Dihydrochloride)
- Packaging
- 2mg
- Price
- $147
- Updated
- 2021/12/16
- Product number
- 3422DW
- Product name
- E6446(Dihydrochloride)
- Packaging
- 1g
- Price
- $1906
- Updated
- 2021/12/16
- Product number
- CD31003814
- Product name
- E6446dihydrochloride
- Purity
- 98+%
- Packaging
- 50mg
- Price
- $2072
- Updated
- 2021/12/16
- Product number
- A119560
- Product name
- E-6446Dihydrochloride
- Purity
- 98%
- Packaging
- 1g
- Price
- $8397
- Updated
- 2021/12/16
- Product number
- AS439180
- Product name
- E-6446Dihydrochloride
- Purity
- 98%
- Packaging
- 2mg
- Price
- $176
- Updated
- 2021/12/16
E6446 (dihydrochloride) Chemical Properties,Usage,Production
Uses
E6446 is a synthetic antagonist of nucleic acid-sensing TLRs. , In vitro, low doses of E6446 specifically inhibited the activation of human and mouse TLR9. Tenfold higher concentrations of this compound also inhibited the human TLR8 response to single-stranded RNA. In vivo, therapy with E6446 diminished the activation of TLR9 and prevented the exacerbated cytokine response observed during acute Plasmodium infection. Furthermore, severe signs of ECM, such as limb paralysis, brain vascular leak, and death, were all prevented by oral treatment with E6446.
E6446 (dihydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
E6446 (dihydrochloride) Suppliers
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
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- Advantage
- 58
- Tel
- +1 (732)236-3202
- sales@cckinase.com
- Country
- United States
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- 58
- Tel
- +1-631-485-4226
- Fax
- 1-631-614-7828
- inquiry@bocsci.com
- Country
- United States
- ProdList
- 19553
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- 58
- Tel
- +1-833-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 57511
- Advantage
- 58
- Tel
- +1-781-999-5354
- support@targetmol.com
- Country
- United States
- ProdList
- 19973
- Advantage
- 58
- Tel
- 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 9926
- Advantage
- 65
View Lastest Price from E6446 (dihydrochloride) manufacturers
- Product
- E6446 (dihydrochloride) 1345675-25-3
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99。99%
- Supply Ability
- 200kg
- Release date
- 2019-12-24